Citicoline Supplement Manufacturer
A clinically studied nootropic — HPLC purity 98%+, generic or branded, blends built to your stack.
INGREDIENT SPOTLIGHT
Citicoline Supplement Manufacturing — A Clinically Studied Nootropic, Run to Spec
We manufacture citicoline (CDP-choline) products on our partner lines in Zhengzhou, China. Citicoline is one of the most clinically studied nootropics — a water-soluble compound that supports brain cell membranes and acetylcholine production. Bring your target dose and format, and we convert it into a specification we can run in bulk.
- HPLC purity confirmed on incoming inspection for every lot
- Capsule, tablet and powder formats
- Branded (Cognizin-grade) or generic CDP-choline, both quotable
Citicoline sodium (CDP-choline, CAS 33818-15-4) at 98%+ HPLC purity — a dual-mechanism cognitive ingredient supported by decades of clinical use across Europe and Japan.
12 Dosage Forms
Gummies, capsules, softgels, tablets, powders, liquids and solid beverages — all run in-house.
6 Production Lines
Two GMP facilities covering 14,000 sqm, 200+ employees, no subcontracted fill.
100+ Export Markets
cGMP, HACCP, ISO 22000 and HALAL certified. Documentation built for your market.
At a Glance
| Item | What We Run |
|---|---|
| Full name | Citicoline (CDP-choline); commonly supplied as citicoline sodium |
| CAS | 33818-15-4 (citicoline sodium) |
| Purity | 98%+ by HPLC as standard; branded (Cognizin-grade) at 99%+ available |
| Form supplied | White crystalline powder, freely water-soluble |
| Common formats | Hard capsule, tablet, powder, stick pack |
| Typical load | 250–500 mg per serving in supplements; clinical use ranges 500–1,000 mg |
| Key mechanism | Supports brain cell membrane phospholipids and acetylcholine production |
| Documentation | COA with HPLC purity, residual solvent, heavy metals, microbiological |
Why Purity and Delivery Both Matter
Citicoline is a well-mapped, clinically studied nootropic. Three decisions decide whether the supplement position is credible.
Purity
Citicoline has been a prescription medicine in Europe and Japan since the 1970s and is now a mainstream nootropic. The supplement spec is strict: HPLC purity with 98%+ the working standard, and branded material such as Cognizin above 99% for a clinically studied, trademarked ingredient.
Delivery
As a synthesised, water-soluble active it is easier to handle than many botanicals, but still needs consistent particle size for uniform blending and a fill that protects it through shelf life. Capsules carry the dose cleanly; tablets and stick packs need a moisture-barrier approach.
Positioning
Citicoline is non-stimulant, so it pairs cleanly with caffeine for focus, choline sources for memory, or omega-3 DHA for synapse support. We quote a single active or a finished nootropic blend built around it.
Formats We Run
Hard capsules
HPMC or gelatin, 250–500 mg fill, the standard format with clean dosing
Tablets
compressed and film-coated, up to 500 mg
Powder and stick packs
3–30 g servings, needs a moisture-barrier pack and a stability study
Blends
citicoline paired with caffeine, choline sources or omega-3 DHA for focus and memory stacks
What We Check Before Release
HPLC purity confirmed against your specification
HPLC purity confirmed against your specification, typically 98%+ (or 99%+ for branded material)
Residual solvent panel appropriate to th…
Residual solvent panel appropriate to the synthesis route
Heavy metals and microbiological limits …
Heavy metals and microbiological limits on the finished product Particle size and blend uniformity for consistent fill weight
Stability study under your intended pack
Stability study under your intended pack, rather than an assumed shelf life Packaging integrity, including desiccant and barrier film where the format requires it
Sourcing and Specification Notes
Generic CDP-choline and branded (Cognizin-grade) citicoline are both available
Generic CDP-choline and branded (Cognizin-grade) citicoline are both available, with different price points and documentation
Citicoline is freely water-soluble
Citicoline is freely water-soluble, which widens the range of delivery formats Purity above 99% narrows the supplier pool and extends lead time
Branded material carries trademark licen…
Branded material carries trademark licensing terms — we will state these before quoting We check the destination market’s regulatory position before sourcing, not after
One Thing Buyers Get Wrong
Assuming “citicoline” always means the same thing. CDP-choline is sold as generic and as branded, trademarked material such as Cognizin. They are chemically the same molecule, but the documentation, price and marketing rights differ. We state which one we are quoting before you commit. Buying on a purity claim without a residual solvent result. Citicoline is synthesised, so the solvent profile is part of the specification. A supplier who cannot show it has not finished the paperwork. Choosing a format without a blend-uniformity check. Citicoline must be blended evenly at 250–500 mg per unit. We verify blend uniformity and fill weight rather than assuming the powder distributes itself.
Popular Formulas We Run
Citicoline is a cognitive staple — the nootropic pairing sets the angle.
Focus + Citicoline
Citicoline 250–500 mg with lion's mane for cognitive support.
Nootropic Stack
Citicoline with alpha-GPC and bacopa for a broad brain formula.
Brain + Omega
Citicoline with omega-3 for a brain-nutrition capsule.
MOQ, Sampling & Lead Times
The commercial basics up front — minimums, sampling and production speed, the same commitment on every ingredient line.
Minimum Order Quantities
From 100 pieces per SKU on standard formats; 500 for custom packaging, 1,000 for a custom formula and 3,000 for full turnkey projects.
Quote & Sampling
Enquiries answered within 24 hours and quotations within 48. Samples take 2-3 days, with pilot batches from 1–5 kg before any bulk commitment.
Production & Dispatch
Standard bulk runs complete in 5–10 days, with packaged goods leaving the factory in 10–15 days after PO and artwork approval.
Where to Go Next
Health Focus
Frequently Asked Questions
Can you supply citicoline?
Yes, at 98%+ HPLC purity as standard, with branded (Cognizin-grade) material at 99%+ available on request. Tell us the target dose, format and destination market and we will confirm feasibility and quote it.
What purity do you supply?
98%+ by HPLC is the working standard for a supplement position. Branded material such as Cognizin sits above 99% and carries the clinical study backing — we quote the purity figure you will see on the Certificate of Analysis.
What is a common citicoline dose?
250–500 mg per serving is the common supplement range, with clinical use running 500–1,000 mg. We match the load to your formula and confirm it on the COA.
What is the difference between generic and Cognizin citicoline?
They are the same molecule, but Cognizin is a trademarked, fermentation-produced grade with a larger clinical study portfolio and a price premium. Generic CDP-choline is chemically identical when verified by COA. We state which we are quoting and the trademark terms before you commit.
Which formats do you run?
Hard capsules, tablets, powders and stick packs, plus finished nootropic blends built around citicoline. Capsules are the most common format because they carry the dose cleanly.
How long does bulk production take?
We reply to enquiries within 24 hours and send a quotation within 48. Samples take 2-3 days, and standard bulk runs complete in 5–10 days with packaged goods leaving in 10–15 days.
What is the minimum order quantity for citicoline?
MOQ is confirmed per format and specification at quotation stage. A standard capsule or tablet run starts from our standard 100-piece MOQ per SKU, rising with custom packaging, custom formulation and turnkey programmes.
DOSAGE FORMS
Which format should your citicoline product take?
The same citicoline dose can be delivered as a capsule, tablet or powder, and each choice changes the fill weight, taste profile and tooling. Because it is water-soluble, citicoline is one of the most flexible nootropics to run.
- Forms we run for this ingredient: capsules, tablets and powders
- Pilot batch from 1–5 kg before any bulk commitment
- Fill weight, unit count and pack format set to your brief
Request a Citicoline Sample
Send the target dose, dosage form and pack size. We reply with a feasibility view, a sample plan and indicative pricing within 1–2 business days.
Start Your Project
Send the format, target active load and destination market. We confirm feasibility, quote it and prepare a sample — usually within 1–2 business days. Prefer to see the capability first? Read how our OEM programmes run, or request a free quote.